The most widely used GLP-1 RAs today and those currently attributed with the most clinical evidence in weight management include Liraglutide, Semaglutide, and Tirzepatide (as a dual agonist of GLP-1 and glucose-dependent insulinotropic polypeptide) [25]
Both semaglutide and fasting have unique ways of influencing hormones and metabolic processes that control appetite, hunger, and energy use
More patients are now exploring medications like semaglutide and tirzepatide as part of a medically supervised approach to weight management
However, they act as passive AT, mainly in that they sequester transition metal ions, preventing RS formation
Review of current medications and health conditions to ensure suitability
Understanding realistic expectations helps patients make informed decisions about their weight loss journey